Ascend Venture Capital is a venture capital firm based in the Central West End neighborhood of St. Louis, MO. The firm focuses on various stages of investment, including Convertible Notes, Seed, Series A, Pre-Seed, and Series B rounds. Ascend partners with founders to provide both financial and operational support, aiding in their journey toward scalable growth.

Notable portfolio companies include Arbol, Avante, DeFi Devs, FreightWaves, infinite io, Insurdata, LO3 Energy, MetaSoul, and StoryFit. Ascend's investment philosophy emphasizes close collaboration with founders to ensure successful scaling. The firm offers unique value-add services that extend beyond capital, focusing on operational support to help startups achieve their growth objectives.