
Actinide builds U.S. electromagnetic isotope separators and demonstrated research-scale HALEU enrichment.
Actinide’s commercial flagship is enriched ytterbium-176 produced on Endurance, a modern electromagnetic isotope separator that sorts ions by mass. The company reports commercial shipments to Oklo Isotopes and more than 95% ytterbium-176 enrichment on that line.
In August 2026, Actinide reconfigured Endurance to enrich natural uranium and reported research-scale high-assay low-enriched uranium assayed at 15.38% uranium-235 by an ISO/IEC 17025 laboratory. Fortitude, its second-generation separator, is intended to expand domestic throughput for medicine, energy, and advanced materials.
Demand for specialized isotopes spans radiopharmaceuticals, advanced nuclear fuel, semiconductors, and quantum systems, while U.S. civilian enrichment still relies heavily on foreign suppliers. The Department of Energy’s HALEU Availability Program states that HALEU is not currently available from domestic commercial suppliers at the scale advanced reactors need.
Actinide’s configurable electromagnetic approach aims at smaller, redeployable capacity that can serve high-value medical isotopes first and nuclear applications as licensing and scale allow. Research-scale HALEU at 15.38% uranium-235 does not itself create a commercial fuel supply; Fortitude throughput and licensing will decide how far the model extends.
Actinide’s electromagnetic platform can switch between medical isotopes and uranium enrichment on the same machine, and it reports producing solid HALEU directly rather than uranium hexafluoride that still needs commercial deconversion.
That flexibility and form-factor claim matter while domestic centrifuge HALEU capacity remains limited and federal programs continue to fund conventional enrichment and deconversion buildout. Sustained Fortitude economics and commercial licensing will determine whether the advantage holds beyond research-scale demonstrations.