
Alumis pioneers precision medicines to improve lives by targeting immune-mediated diseases with optimized, transformative therapies.
alumis.comCrawled Oct 15, 2026
A-005 is the first allosteric tyrosine kinase 2 (TYK2) inhibitor with demonstrated ability to cross the human blood-brain barrier, enabling targeted treatment within the CNS and periphery.
ESK-001 is a highly selective, next-generation oral tyrosine kinase 2 (TYK2) inhibitor designed to correct immune dysregulation across a range of diseases, including plaque psoriasis.
ESK-001 is a highly selective, next-generation oral tyrosine kinase 2 (TYK2) inhibitor designed to correct immune dysregulation across a range of diseases, including SLE.
Lonigutamab is a next-generation anti–insulin-like growth factor 1 receptor (anti-IGF-1R) —a humanized IgG1 monoclonal antibody designed for subcutaneous delivery.
The company is developing lonigutamab, an anti–insulin-like growth factor 1 receptor (anti-IGF-1R) monoclonal antibody (mAb).
The company is developing oral TYK2 inhibitors ESK-001 and A-005 for immune-mediated diseases.
The company’s R&D approach targets key drivers of immune dysfunction and uses genetic and translational insights.
The company uses a data analytics platform that integrates genetic, genomic, proteomic, biological, and clinical insights to support a precision approach to therapeutic development.
The company encourages work-life balance and self-care as part of its employee wellness approach.
The company seeks people dedicated to teamwork.
The company aims to replace broad immunosuppression with targeted therapies to improve patients’ lives.
The company uses a precision approach to develop therapies for immune-mediated diseases.
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