MidCap Financial Investment Corporation focuses on middle-market companies, primarily investing through mezzanine and senior secured loans. The firm may also include equity components in its investments. As a business development company, MidCap Financial targets opportunities in various sectors, with a particular emphasis on hospitality-related businesses.

Notable portfolio companies include Renew Financial and ZPower, a battery technology company. MidCap Financial has participated in both debt financing and equity rounds, demonstrating flexibility in its investment approach. The firm's strategy aims to provide capital solutions tailored to the needs of growing middle-market businesses, leveraging its expertise in hospitality and other sectors to support portfolio companies' growth.