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EvolutionaryScale
Developer of frontier AI models for the life sciences, including protein models used to understand and design proteins.
Founded
2023Developer of frontier AI models for the life sciences, including protein models used to understand and design proteins.
EvolutionaryScale develops frontier AI models for the life sciences, centered on protein language models that reason over protein sequence, structure, and function. Scientists access the models through the Forge API platform and through open-weight, MIT-licensed releases.
The company also offers specialized commercial versions aimed at drug design. After November 2025, access is presented through the Biohub platform.
The company targets scientific and pharmaceutical demand for protein design across drug discovery, antibody engineering, industrial enzymes, and clean energy. Management framed the opportunity as long-horizon, with roughly a decade to reach therapies.
AI-for-biology competition was crowded at launch. The November 2025 transition folded the effort into nonprofit Biohub, organized around four grand challenges and a tenfold compute expansion by 2028.
The founding team pioneered protein language modeling at Meta AI, and lead investor Nat Friedman described them as the team that invented protein language modeling. The company trained its largest model run with over 10^24 FLOPS of compute, per its release post.
Distribution is dual-track, combining open-weight MIT-licensed releases with a hosted API. After November 2025, the nonprofit Biohub platform is expanding compute to 10,000 GPUs by 2028.
TechCrunch reported profitability could be far off, citing the company's own pitch-deck view that generative-AI-designed therapies could take about a decade. At launch it faced well-resourced AI-biology competitors including Isomorphic Labs, Insitro, Recursion, and Inceptive.
As a public benefit company, its commercialization rested on partnerships, usage fees, and revenue sharing. The November 2025 Biohub team hire ended its run as an independent startup.