
Kallyope is a New York City biotechnology company developing medicines from neural signaling insights.
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The Klarity Platform uses integrated technologies to provide insights into neural circuits involved in migraine and metabolism.
The Klarity Platform uses integrated technologies to provide insights into neural circuits involved in migraine and metabolism.
The company is developing programs targeting neural circuits for migraine treatment.
View the latest news about advances at Kallyope.
Novel mechanism of TRPM8 antagonism may offer new option for large number of patients suffering from debilitating migraines Full data to be presented at a
Results contribute to growing body of evidence in support of elismetrep, a TRPM8 migraine-associated channel blocker (MACB), to help address the
Clinically meaningful data establishes proof of concept for elismetrep as a promising therapeutic candidate for migraine and its progression into
The company provides a contact form for messages.
Kallyope outlines its 2026 strategic priorities for its migraine and metabolism portfolio, built on its neural circuits platform. The portfolio includes elismetrep and K-554.
Jan 2026 · KallyopeNews article
Kallyope reports positive results from a Phase 2b study of elismetrep for acute migraine treatment. Elismetrep is an oral, selective TRPM8 channel blocker.
Dec 2025 · KallyopeNews article
Kallyope raises a $236 million Series D financing round to advance its gut-brain axis programs. The announcement provides the round size and broad research focus but does not name participating investors or describe individual programs, development plans, or specific milestones.
Feb 2022 · BioSpaceNews article
Kallyope advances its gut-brain axis treatment programs following a Series D financing. The report gives no financing amount or further details about the treatment programs.
Feb 2022 · Pharmaceutical TechnologyNews article