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AddedJul 4, 2026
UpdatedJul 4, 2026
Nucleo

Nucleo

Agentic platform automating CT scan analysis for oncology care and clinical research.

HQ
San Francisco, CA, US
Founded
2025
Accelerator
Y Combinator logoY CombinatorF25
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Contents

  1. 01Products & Services
  2. 02Market Outlook
  3. 03Competitive Strengths
  1. 01Products & Services
  2. 02Market Outlook
  3. 03Competitive Strengths

Product Overview

Nucleo's platform ingests CT scans and applies machine-learning segmentation to automate body composition and sarcopenia assessment, tumor lesion sizing, and target vs non-target lesion classification under RECIST criteria.

The system is positioned as an agentic oncology diagnostics layer for oncologists and radiologists, with validation studies reporting 98% agreement with medical experts and segmentation 2,500 times faster than manual workflows.

Market Outlook

Nucleo targets the oncology imaging workflow, where delayed manual analysis can extend the time between cancer diagnosis and treatment. By automating CT scan segmentation and RECIST classification, the company aims to compress diagnostic and treatment-planning intervals that currently stretch to 9-11 weeks in the United States.

Its initial deployments are in academic medical centers, including Stanford Hospital, Cedars-Sinai, UCI Health, and Weill Cornell, positioning the platform as a clinical decision-support and research tool in both patient care and oncology trials.

Competitive Advantages

Nucleo cites speed and expert agreement as core advantages: its segmentation runs 2,500 times faster than manual measurement and its validation studies show 98% agreement with medical experts.

The company also reports state-of-the-art sarcopenia detection performance and hospital collaborations with Stanford Hospital, Cedars-Sinai, UCI Health, and Weill Cornell.