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OpenEvidence
AddedFeb 17, 2024
UpdatedJun 25, 2026
OpenEvidence

OpenEvidence

Series D

AI-powered clinical decision support platform used by 760,000+ physicians.

HQ
Miami, FL, US
Founded
2021
Overview
Compare
Fundraising
Employees
News
Website

OpenEvidence (Xyla Inc.) is an AI-powered clinical decision support platform that aggregates, synthesizes, and visualizes peer-reviewed medical research for healthcare professionals. Founded in 2021 and headquartered in Miami, Florida, the platform is used by over 760,000 registered physicians—representing more than 40% of U.S. doctors—to stay current with the latest clinical evidence and research literature. The company leverages artificial intelligence and machine learning to combat information overload in medicine and enhance patient care.

OpenEvidence is a Mayo Clinic Platform Accelerate Company and has partnered with Elsevier to launch ClinicalKey AI, integrating trusted content from prominent medical journals and resources. Notable affiliations include Ram Dandillaya of Cedars-Sinai, Antonio Forte of Mayo Clinic, John Lee of Harvard Medical School, and Nobel Laureate Daniel Kahneman. The company has raised approximately $735 million in total funding and was valued at $12 billion as of January 2026, with reported annual recurring revenue of $150 million as of December 2025.

OpenEvidence - Similar Companies

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Outcomes4Me logo

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EvidenceCare logo

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OpenEvidence - Quick Facts

Who are OpenEvidence's competitors?

Companies similar to OpenEvidence include Doctor Evidence, Vera Health, Evidentia Health and Researchably.

When was OpenEvidence founded?

OpenEvidence was founded in 2021.

Where is OpenEvidence's headquarters located?

OpenEvidence's headquarters is located in Miami, FL, US.

When was OpenEvidence's last funding round?

OpenEvidence's most recent funding round was for $250M (USD) in January 2026.

How much has OpenEvidence raised to-date?

As of Jan 21, 2026, OpenEvidence has raised a total of $630M (USD).

How many employees does OpenEvidence have?

OpenEvidence has 30 employees as of May 10, 2026.

OpenEvidence - Classification

Industry
  • Bioinformatics Organizations
  • Medical Organizations
  • Software Companies
Ownership
  • Venture Capital
Technology
  • AI
  • Machine Learning
Geographic Exposure
  • Global
Model
  • Platform
Revenue
  • Recurring
  • SaaS
Customer
  • Enterprise
Main Product
  • Medical Research
Tags
  • AI Operations
  • Healthtech
NAICS
  • 620000Health Care and Social Assistance
SIC
  • 8000Health Services
  • 8040Offices And Clinics Of Other Health Practitioners
  • 8049Offices And Clinics Of Health Practitioners, Not Elsewhere Classified
Show 13 more industry codes
NAICS
  • 513200Software Publishers
  • 540000Professional, Scientific, and Technical Services
  • 541500Computer Systems Design and Related Services
  • 510000Information
  • 513000Publishing Industries
  • 541000Professional, Scientific, and Technical Services
  • 513210Software Publishers
  • 541510Computer Systems Design and Related Services
  • 541511Custom Computer Programming Services
SIC
  • 7300Business Services
  • 7370Computer Programming, Data Processing, And Other Computer Related
  • 7371Computer Programming Services
  • 7372Prepackaged Software