The University of California-Irvine's Institute for Clinical and Translational Science (ICTS) was established with funding from the National Institutes of Health (NIH) under the Clinical and Translational Sciences Award (CTSA) program. The core mission of ICTS is to accelerate the translation of scientific discoveries into clinical applications to improve public health. The institute offers a range of services including biostatistics, epidemiology, clinical research ethics consultations, community engagement, and specialized support for diverse populations. ICTS focuses on fostering collaborative research efforts and providing educational opportunities to enhance the skills of clinical researchers.

Notable affiliates include leading researchers and faculty from UC Irvine, who contribute to its multidisciplinary approach. The institute has received significant NIH funding, underscoring its importance in the national landscape of medical research. Key achievements include numerous funded grants and successful pilot programs that have advanced clinical practices and community health initiatives. Overall, ICTS has made a substantial impact by bridging the gap between laboratory research and patient care, promoting innovation, and improving health outcomes through its comprehensive support and collaborative efforts.