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Breakout Ventures
AddedFeb 15, 2024
UpdatedJun 28, 2026
Breakout Ventures

Breakout Ventures

Operating

Breakout Ventures: An early-stage fund supporting bold, science-based startups.

Location
San Francisco, CA, US
Founded
2016
Firm
Compare
Portfolio
Fundraising
Employees
Website

Breakout Ventures is an early-stage investment fund focused on supporting bold, science-based startups. The firm typically invests in Seed, Series A, and Series B rounds, with a strong emphasis on companies that leverage scientific innovation to drive their business models. Breakout Ventures seeks to back visionary scientist entrepreneurs who are pioneering new technologies and solutions across various sectors.

Notable portfolio companies include A-Alpha Bio, Canaery, Checkerspot, Cytovale, EnPlusOne Biosciences, Immusoft, Modern Meadow, Parallel Bio, Parthenon Therapeutics, Phantom Neuro, Phylagen, ShiraTronics, Surf Bio, Twelve, Twelve Benefit, and Zymochem. The firm prides itself on its investment philosophy of nurturing groundbreaking scientific ventures and offers unique value-add services to its portfolio companies, such as strategic guidance and access to a robust network of industry experts and partners.

Breakout Ventures - Portfolio Snapshot

Portfolio activity breakdown across disclosed investments and stages

Total Investments24
Current Portfolio Count17
Total Portfolio Exits0

Top Investment Stages

Series A8 (33.3%)
Seed7 (29.2%)
Series B7 (29.2%)
Debt Financing1 (4.2%)
Series Unknown1 (4.2%)

Stage Mix

Series A 33%Seed 29%Series B 29%Debt Financing 4%Series Unknown 4%

Concentration shown as share of disclosed investments by stage.

Recent Investments

Zymochem logo

Zymochem

A-Alpha Bio logo

A-Alpha Bio

Parallel Bio logo

Parallel Bio

EnPlusOne Biosciences logo

EnPlusOne Biosciences

Twelve logo

Twelve

Canaery logo

Canaery

Twelve Benefit logo

Twelve Benefit

Surf Bio logo

Surf Bio

Phantom Neuro logo

Phantom Neuro

Parthenon Therapeutics logo

Parthenon Therapeutics

Cytovale logo

Cytovale

Immusoft logo

Immusoft

Checkerspot logo

Checkerspot

ShiraTronics logo

ShiraTronics

Curie logo

Curie

Phylagen logo

Phylagen

Modern Meadow logo

Modern Meadow

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Breakout Ventures - Classification

Also Known As
  • Breakout Management, LLC
NAICS
  • 520000Finance and Insurance
  • 523000Securities, Commodity Contracts, and Other Financial Investments and Related Activities
  • 523900Other Financial Investment Activities
  • 523990All Other Financial Investment Activities
  • 523999Miscellaneous Financial Investment Activities
SIC
  • 6700Holding And Other Investment Offices
  • 6790Miscellaneous Investing
  • 6799Investors, Not Elsewhere Classified
Show 6 more industry codes
NAICS
  • 525000Funds, Trusts, and Other Financial Vehicles
  • 523910Miscellaneous Intermediation
  • 523940Portfolio Management and Investment Advice
SIC
  • 6000Depository Institutions
  • 6720Investment Offices
  • 6722Management Investment Offices, Open-end