Lightbank is a Chicago-based venture capital firm focusing on disruptive technology investments. The firm primarily invests in seed and early-stage rounds, with a particular interest in social media, consumer web, energy, and life sciences sectors. Lightbank's typical investment ranges from seed to Series B rounds, with a strong emphasis on seed and Series A investments.

Notable portfolio companies include Boom Supersonic, Clearcover, and Sprout Social. Founded by Eric Lefkofsky and Brad Keywell, Lightbank emphasizes a Midwest work ethic, speed, integrity, teamwork, and passion in its investment approach. The firm offers value-add services to portfolio companies, leveraging its founders' entrepreneurial experience and network to support startup growth and success.