MassMutual Impact Investing focuses on technology and sustainability-driven businesses in less-developed regions of Massachusetts, as well as supporting Black-owned businesses. The firm's MassMutual Catalyst Fund targets early-stage investments, primarily participating in Seed and Series A rounds, with occasional involvement in Series B funding.

Notable portfolio companies include Alloy Enterprises, CareAcademy, and Nth Cycle. MassMutual Impact Investing's approach combines financial returns with social impact, aiming to foster economic growth in underserved areas and promote diversity in entrepreneurship. The firm's investments span various sectors, including edtech, cleantech, fintech, and healthcare technology.