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Sphera Global Healthcare Fund
AddedFeb 13, 2024
UpdatedJun 28, 2026
Sphera Global Healthcare Fund

Sphera Global Healthcare Fund

Operating

Sphera Global: A Tel Aviv-based fund management firm offering investment advice and portfolio services globally.

Location
Tel Aviv, Tel Aviv District, IL
Founded
2004
Firm
Compare
Portfolio
Employees
Website

Sphera Global Healthcare Fund, based in Tel Aviv, Israel, is a prominent fund management firm specializing in the healthcare sector. The firm primarily invests in Series B, Series C, and Series E rounds, as well as post-IPO equity, with a focus on both Israeli and U.S. markets. Sphera manages six distinct long/short equity strategies and one real estate private equity fund, leveraging a disciplined, fundamental investing approach overseen by a team of over twenty professionals.

Notable portfolio companies include aTyr Pharma, Deciphera Pharmaceuticals, Frontier Medicines, Immune-Onc Therapeutics, Outlook Therapeutics, and Werewolf Therapeutics. Sphera's investment philosophy emphasizes a repeatable process and deep sector expertise. The firm offers unique value-add services such as strategic guidance and operational support to its portfolio companies, ensuring they have the resources needed to succeed in the competitive healthcare landscape.

Sphera Global Healthcare Fund - Portfolio Snapshot

Portfolio activity breakdown across disclosed investments and stages

Total Investments7
Current Portfolio Count5
Total Portfolio Exits1

Top Investment Stages

Series B4 (57.1%)
Post Ipo Equity1 (14.3%)
Series C1 (14.3%)
Series E1 (14.3%)

Stage Mix

Series B 57%Post Ipo Equity 14%Series C 14%Series E 14%

Concentration shown as share of disclosed investments by stage.

Recent Investments

Outlook Therapeutics logo

Outlook Therapeutics

Frontier Medicines logo

Frontier Medicines

Immune-Onc Therapeutics logo

Immune-Onc Therapeutics

Werewolf Therapeutics logo

Werewolf Therapeutics

Deciphera Pharmaceuticals logo

Deciphera Pharmaceuticals

aTyr Pharma logo

aTyr Pharma

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Sphera Global Healthcare Fund - Classification

Also Known As
  • Sphera Global Healthcare Management, L.P.
NAICS
  • 520000Finance and Insurance
  • 523000Securities, Commodity Contracts, and Other Financial Investments and Related Activities
  • 523900Other Financial Investment Activities
  • 523990All Other Financial Investment Activities
  • 523999Miscellaneous Financial Investment Activities
SIC
  • 6700Holding And Other Investment Offices
  • 6720Investment Offices
  • 6722Management Investment Offices, Open-end
Show 2 more industry codes
NAICS
  • 525000Funds, Trusts, and Other Financial Vehicles
SIC
  • 6000Depository Institutions