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Two Sigma Ventures
AddedFeb 13, 2024
UpdatedJul 16, 2026
Two Sigma Ventures

Two Sigma Ventures

Operating

Two Sigma Ventures: Early-stage venture capital fund investing in data-driven, transformative companies.

Location
New York City, NY, US
Founded
2012
Firm
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Portfolio
Employees
News
Website

Two Sigma Ventures is an early-stage venture capital firm investing in transformative companies harnessing information growth and computing power. They focus on startups leveraging data and engineering to create innovative solutions across various sectors. The firm typically invests in seed and Series A rounds, with occasional participation in later stages.

Notable portfolio companies include Insitro, Socure, Remote, and Recursion Pharmaceuticals. Two Sigma Ventures offers patient financial capital and expert human capital to entrepreneurs, emphasizing their commitment to supporting startups beyond just funding. Their investment philosophy centers on technologies that unlock human potential, enable breakthrough therapies, and foster human interaction through artificial intelligence.

Two Sigma Ventures - Portfolio Snapshot

Portfolio activity breakdown across disclosed investments and stages

Total Investments139
Current Portfolio Count65
Total Portfolio Exits5

Top Investment Stages

Series A40 (32.0%)
Seed31 (24.8%)
Series B30 (24.0%)
Series C14 (11.2%)
Series Unknown10 (8.0%)

Stage Mix

Series A 32%Seed 25%Series B 24%Series C 11%Series Unknown 8%

Concentration shown as share of disclosed investments by stage.

Recent Investments

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Freeform logo

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Osmo logo

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Rive logo

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Enveda Biosciences logo

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Cajal Neuroscience logo

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Hexagon Bio logo

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Flatfile logo

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Xilis logo

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Isabl logo

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Tive logo

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Remote logo

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Okteto logo

Okteto

Timescale logo

Timescale

Kallyope logo

Kallyope

Terray Therapeutics logo

Terray Therapeutics

Rift Finance logo

Rift Finance

Radar logo

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Two Sigma Ventures - Classification

NAICS
  • 520000Finance and Insurance
  • 523000Securities, Commodity Contracts, and Other Financial Investments and Related Activities
  • 523900Other Financial Investment Activities
  • 523990All Other Financial Investment Activities
  • 523999Miscellaneous Financial Investment Activities
SIC
  • 6700Holding And Other Investment Offices
  • 6790Miscellaneous Investing
  • 6799Investors, Not Elsewhere Classified
Show 6 more industry codes
NAICS
  • 525000Funds, Trusts, and Other Financial Vehicles
  • 523910Miscellaneous Intermediation
  • 523940Portfolio Management and Investment Advice
SIC
  • 6000Depository Institutions
  • 6720Investment Offices
  • 6722Management Investment Offices, Open-end