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Through the use of customized DNA/RNA sequences, researchers in the laboratory of KI member Timothy Lu have designed a synthetic gene circuit that is activated by transcriptional signals expressed by tumor cells, triggering a combinatorial immune response.
A collaborative Bridge Project team describe a novel strategy for inhibiting Mcl-1, a protein that is often overexpressed in cancer and contributes to tumor cell survival and resistance to chemotherapy.
Forest White has begun applying his signature analytical techniques to investigate how environmental factors affect cancer development and progression.
Robert Langer on the power of curiosity-driven science. Caution for keto diets. Remembering Susumu Tonegawa.
The Koch Institute announced four new extramural faculty members: Regina Barzilay, Ed Boyden, Jeremiah Johnson, and Alex Shalek.
The BioConvergence Cancer Alliance at MIT’s Koch Institute added Future Health – A Global Initiative by Abu Dhabi as a founding member. The partnership will foster collaboration on cancer prevention, earlier detection, and treatment.
The MIT Center for Precision Cancer Medicine launched within the KI and was established by a major gift from an anonymous donor.
“The freedom to choose a scientific direction, and in close proximity to the best scientists of the world, is immensely gratifying. Not only am I able to advance my career as a scientist, but I am fortunate enough to help others who dream of being a scientist, like I did many years ago.”
Koch Institute Clinical Investigators connect research with clinical challenges and solutions. The program lets physician-scientists conduct cancer research while practicing medicine and gives Koch Institute researchers insight into cancer treatment challenges.
Andrea Califano, PhD Columbia University
Professor Anderson develops devices, materials, and vaccines to create customizable living and gene therapies for cancer, diabetes, and other applications.
Koch Institute research combines MIT’s rich traditions of interdisciplinary inquiry and technological innovation with the most advanced investigation into the fundamental biology of cancer.
Credit: Courtesy of Ellenzweig, Architect
Salvador Luria, Nancy Hopkins, David Baltimore, ca. 1974
A liver cell with a multipolar spindle (green) pulls chromosomes (blue) in many directions. Studying cell division in the liver could provide insight into how this process is exploited or disrupted in cancer. Credit: Kristin Knouse (2014 Image Awards winner)
The Koch Institute is an NCI-designated Basic Cancer Research Center and a hub for cancer research on the MIT campus. Its facility brings together biologists, chemists, engineers, computer scientists, and clinicians for interdisciplinary cancer research.