Cytel Synthetic Control Arms designs synthetic control arms from real-world data for clinical trials.
Cytel Synthetic Control Arms is a specialty service that constructs synthetic control arms from real-world data to support clinical trial design and regulatory submissions. The offering applies propensity scoring, Bayesian dynamic borrowing, and statistical weighting, integrating homogenous and heterogeneous historical data into tailored comparators. It addresses enrollment challenges, ethical concerns, and molecularly defined populations where concurrent controls are infeasible.
The service covers single-arm contextualization, hybrid designs, and health technology assessment support across oncology and non-oncology indications. Cytel pairs the methods with regulatory strategy guidance, positioning synthetic controls as interpretable evidence for accelerated therapy development.
