National Interstate Insurance Company is a specialty property and casualty insurer focused on commercial transportation, writing auto liability and physical damage, workers' compensation, general liability, motor truck cargo, and property and inland marine coverage. Through its National Interstate and Vanliner brands, it also provides alternative risk transfer and group captive programs for fleets, including moving and storage and last mile delivery operators.

The company differentiates through niche underwriting, in-house loss control, and claims handling tailored to individual transportation segments. It serves fleet trucking, motorcoach and school bus, limousine, paratransit and non-emergency medical transport, ambulance, propane hauling, waste, and crane and specialized carrier operators, reaching them through a national producer network.