ExoPTEN is a cell-free treatment being developed for acute spinal cord injury to promote neural repair.
ExoPTEN combines a minimally invasive, cell-free method with preclinical evidence of functional recovery following a short intranasal treatment cycle and is designed to support neural repair through its promotion. In early studies, the treatment cycle was associated with nerve regeneration, neural regrowth, and recovery of key functions including movement, sensation, and bladder control. Further dose-ranging studies using objective gait analysis showed dose-dependent improvements in walking quality, balance, coordination, and weight support.
ExoPTEN is being developed for patients who suffered a recent acute spinal cord injury. Current care stabilizes the injury, prevents further damage and supports rehabilitation, but cannot reliably rebuild lost connections.
