KariusKarius Spectrum

Karius Spectrum is a plasma-based metagenomic sequencing test that detects microbial cell-free DNA from more than 1,000 bacteria, fungi, parasites and DNA viruses from a single blood draw. Performed as a laboratory-developed test in a CLIA-certified, CAP-accredited laboratory, it reports quantitative results typically the next day after sample receipt.

The test is designed for hospitalized and immunocompromised patients with suspected deep-seated or difficult-to-diagnose infections, including pneumonia, febrile neutropenia and fever of unknown origin. Optional bacterial antimicrobial resistance marker detection helps clinicians tailor antimicrobial therapy sooner than conventional culture-based methods allow.